Abteilung Endokrinologie, Onkologie und Knochenstoffwechsel



  • Krause R, Stange R, Roth HJ, Kaase H, Michalsen A, Holick MF. Partial body UV exposure in chronic kidney disease and extrarenal Vitamin D metabolism. Anticancer Research 2018 38: 1217 – 1219
  • Haap M, Roth HJ, Huber T, Dittmann H, Richard Wahl. Urinary iodine: comparison of a simple method for ist determination in microplates with measurement by inductively coupled plasma mass spectrometry. Scientific Reports 2017; 7:39835 DOI: 10.1038/srep39835


  • Krause R, Roth HJ, Kaase H, Stange R, Holick MF. Vitamin D Status in Chronic Kidney Disease – UVB Irradiation Is Superior to Oral Supplementation. ANTICANCER RESEARCH 2016; 36: 1397-1402
  • Rief H, Omlor G, Akbar M, Bruckner T, Rieken S, Förster R, Schlampp I, Welzel T, Bostel T, Roth HJ, DebusJ. Biochemical markers of bone turnover in patients with spinal metastases after resistance training under radiotherapy – a randomized trial BMC Cancer (2016) 16:231


  • Jungert A, Roth HJ, Neuhäuser-Berthold M. Associations of serum 25-hydroxycholecalciferol and parathyroid hormone with serum lipids differ by sex and vitamin D status. Public Health Nutr. 2015 Jun;18(9):1684-9
  • Belavý DL, Baecker N, Armbrecht G, Beller G, Buehlmeier J, Frings-Meuthen P, Rittweger J, Roth HJ, Heer M, Felsenberg D. Serum sclerostin and DKK1 in relation to exercise against bone loss in experimental bed rest. J Bone Miner Metab. 2015 Jun 9. [Epub ahead of print]


  • Scholze A, Liu Y, Pedersen L, Xia S, Roth HJ, Hocher B, Rasmussen LM, Tepel M. Soluble α-klotho and its relation to kidney function and fibroblast growth factor-23. J Clin Endocrinol Metab. 2014 May;99(5):E855-61
  • Zawada AM, Rogacev KS, Hummel B, Berg JT, Friedrich A, Roth HJ, Obeid R, Geisel J, Fliser D, Heine GH. S-adenosylhomocysteine is associated with subclinical atherosclerosis and renal function in a cardiovascular low-risk population. Atherosclerosis. 2014 May;234(1):17-22
  • Miokovic T, Armbrecht G, Gast U, Rawer R, Roth HJ, Runge M, Felsenberg D, Belavý DL. Muscle atrophy, pain, and damage in bed rest reduced by resistive (vibration) exercise. Med Sci Sports Exerc. 2014 Aug;46(8):1506-16
  • Jungert A, Roth HJ, Neuhäuser-Berthold M. Associations of serum 25-hydroxycholecalciferol and parathyroid hormone with serum lipids differ by sex and vitamin D status. Public Health Nutrition doi:10.1017/S1368980014002286 Published online: 30 October 2014
  • Wielders JP, Carter GF, Eberl H, Morris G, Jürgen Roth H, Vogl C. Automated Competitive Protein-Binding Assay for Total 25-OH Vitamin D, Multicenter Evaluation and Practical Performance. J Clin Lab Anal. 2014 Aug 17. doi: 10.1002/jcla.21793
  • Seiler S, Rogacev KS, Roth HJ, Shafein P, Emrich I, Neuhaus S, Floege J, Fliser D, Heine GH. Associations of FGF-23 and sKlotho with Cardiovascular Outcomes among Patients with CKD Stages 2–4. Clin J Am Soc Nephrol 2014;9:1049–1058.
  • Scharnholz B, Gilles M, Marzina A, Kommer M, Lederbogen F, Wudy SA, Hartmann MF, Westphal S, Roth HJ, Kahl KG, Meyer-Lindenberg A, Michaely HJ, Deuschle M. Do depressed patients without activation of the hypothalamus-pituitary-adrenal (HPA) system have metabolic disturbances? Psychoneuroendocrinology. 2014 Jan;39:104-10


  • Tepel T, Armbruster FP, Grön HJ, Scholze A, Reichetzeder C, Roth HJ, Hocher B. Nonoxidized, Biologically Active Parathyroid Hormone Determines Mortality in Hemodialysis Patients. J Clin Endocrinol Metab 2013;98(12): 4744-51
  • Hocher B, Oberthür D, Slowinski T, Querfeld U, Schaefer F, Doyon A, Tepel M, Roth HJ, Grön HJ, Reichetzeder C, Betzel C, Armbruster FP. Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients. Kidney Blood Press Res 2013; 37: 240-251
  • von Eckardstein A, Roth HJ, Jones G, Preston S, Szekeres T,Imdahl R, Conti M, Blanckaert N, Jose D, Thiery J, Feldmann L, von Ahsen N, Locatelli M, Kremastinou J, Kunst A, Hubbuch A, McGovern M. cobas 8000 Modular Analyzer Series Evaluated under Routine-like Conditions at 14 Sites in Australia, Europe, and the United States. J Lab Autom 2013; 18(4): 306-327
  • Biglari B, Büchler A, Swing T, Biehl E, Roth HJ, Bruckner T, Schmidmaier G, Ferbert T, Gerner HJ, Moghaddam A. Increase in soluble CD95L during subacute phases after human spinal cord injury: a potential therapeutic target. Spinal Cord. 2013 Mar; 51(3): 183-7


  • Jungert A, Roth HJ, Neuhäuser-Berthold M. Serum 25-hydroxyvitamin D3, parathyroid hormone and blood pressure in an elderly cohort from Germany: a cross-sectional study. Nutrition & Metabolism 2012 Mar 21;9(1):20
  • Lecei O, Lederbogen F, Gronau W, Scharnholz B, Terhardt J, Schilling C, Gilles M, Kopf D, Roth HJ, Weber-Hamann B, Deuschle M. Treatment with mirtazapine and venlafaxine increases noradrenaline excretion in depressed patients. J Clin Psychopharmacol. 2012 Aug;32(4):574-6
  • Jaeger BAS, Tauer JT, Ulmer A, Kuhlisch E, Roth HJ, Meinolf Suttorp M. Changes in bone metabolic parameters in children with chronic myeloid leukemia on imatinib treatment. Med Sci Monit, 2012; 18(12): CR721-728
  • Unger N, Hinrichs J, Deutschbein T, Schmidt H, Walz MK, Mann K, Petersenn S. Plasma and Urinary Metanephrines Determined by an Enzyme Immunoassay, but not Serum Chromogranin A for the Diagnosis of Pheochromocytoma in Patients with Adrenal Mass. Exp Clin Endocrinol Diabetes 2012; 120: 494–500
  • Seiler S, Wen M, Roth HJ, Fehrenz M, Flügge F, Herath E, Weihrauch A, Fliser D,Heine GH. Plasma Klotho is not related to kidney function and does not predict adverse outcome in patients with chronic kidney disease. Kidney Int 2012 August 15
  • Hocher B, Armbruster FP, Stoeva S, Reichetzeder C, Grön HJ, Lieker I, Khadzhynov D, Slowinski T, Roth HJ. Measuring Parathyroid Hormone (PTH) in Patients with Oxidative Stress – Do We Need a Fourth Generation Parathyroid Hormone Assay? PLoS ONE 2012; 7(7): e40242
  • Belavý DL, Seibel MJ, Roth HJ, Armbrecht G, Rittweger J, Felsenberg D. The effects of bed-rest and countermeasure exercise on the endocrine system in male adults: Evidence for immobilization-induced reduction in sex hormone-binding globulin levels. J. Endocrinol. Invest.2012; 35: 54-62
  • Jungert A, Roth HJ and Neuhauser-Berthold M. Serum 25-hydroxyvitamin D3 and body composition in an elderly cohort from Germany: a cross-sectional study. Nutrition & Metabolism 2012, 9:42
  • Krause R, Schober-Halstenberg HJ, Edenharter G, Haas K, Roth HJ, Frei U. Vitamin D status and mortality of german hemodialysis patients. Anticancer Res. 2012 Jan;32(1):391-5
  • Bock O, Börst H, Beller G, Armbrecht G, Degner C, Martus P, Roth HJ, Felsenberg D. Impact of oral ibandronate 150mg once monthly on bone tructure and density in postmenopausal osteoporosis or osteopenia derived from in vivo μCT. Bone. 2012 Jan;50(1):317-24


  • Brandenburg VM, Fliser D, Fliser M, Floege J, Galle J, Girndt M, Haufe CC, Ketteler M, Wanner C. Praxisleitfaden zur Therapie des sHPT. Nephrologe 2011;6:274-276
  • Felsenberg D, Bock O, Börst H, Armbrecht G, Beller G, Degner C, Stephan-Oelkers M, Schacht E, Mazor Z, Hashimoto J, Roth HJ, Martus P, Runge M. Additive impact of alfacalcidol on bone mineral density and bone strength in alendronate treated postmenopausal women with reduced bone mass. J Musculoskelet Neuronal Interact 2011; 11(1):34-45
  • Leidig-Bruckner G, Roth HJ, Bruckner T, Lorenz A, Raue F, Frank-Raue K. Are commonly recommended dosages for vitamin D supplementation too low? Vitamin D status and effects of supplementation on serum 25-hydroxyvitamin D levels-an observational study during clinical practice conditions. Osteoporos Int. 2011 Jan;22(1):231-40.
  • Brandhorst G, Streit F, Kratzsch J, Schiettecatte J, Roth HJ, Luppa PB, Körner A, Kiess W, Binder L, Oellerich M, von Ahsen N. Multicenter evaluation of a new automated electrochemiluminesscence immunoassay for the quantification of testosterone compared to liquid chromatography tandem mass spectrometry. Clin Biochem 2011; 44: 264-67.


  • Moghaddam A, Müller U, Roth HJ, Wentzensen A, Grützner PA, Zimmermann G. TRACP 5b and CTX as osteological markers of delayed fracture healing. Injury. 2010 Dec 16. [Epub ahead of print]
  • Armbrecht G, Belavý DL, Gast U, Bongrazio M, Touby F, Beller G, Roth HJ, Perschel FH, Rittweger J, Felsenberg D. Resistive vibration exercise attenuates bone and muscle atrophy in 56 days of bed rest: biochemical markers of bone metabolism. Osteoporos Int. 2010; 21(4);597-607


  • Graser A, Stieber P, Nagel D, Schaefer C, Horst D, Becker CH R, Nikolaou K, Lottes A, Geisbuesch S, Kramer H, Wagner AC, Diepolder H, Schirra J, Roth HJ, Seidel D, Goeke B, Reiser MF, Kolligs F T. Comparison of CT Colonography, Colonoscopy, Sigmoidoscopy, and fecal occult blood tests for the detection of advanced adenoma in an average risk population. GUT 2009 Feb;58(2):241-8
  • Hermsen D, Broecker-Preuss M, Casati M, Mas JC, Eckstein A, Gassner D, van Helden J, Inomata K, Jarausch J, Kratzsch J, Mann K, Miyazaki N, Navarro Moreno MA, Murakami T, Roth HJ, Noh JY, Scherbaum WA, Schott M. Technical evaluation of the first fully automated assay for the detection of TSH receptor autoantibodies. Clin Chim Acta 2009; 401(1-2):84-9.
  • Schott M, Hermsen D, Broecker-Preuss M, Casati M, Mas JC, Eckstein A, Gassner D, Golla R, Graeber C, van Helden J, Inomata K, Jarausch J, Kratzsch J, Miyazaki N, Moreno MA, Murakami T, Roth HJ, Stock W, Noh JY, Scherbaum WA, Mann K. Clinical value of the first automated TSH receptor autoantibody assay for the diagnosis of Graves' disease: an international multicentre trial. Clin Endocrinol (Oxf). 2009; 71(4):566-73.
  • Giannitsis E, Roth HJ, Leithäuser RM, Scherhag J, Beneke R, Katus HA. New Highly Sensitivity Assay Used to Measure Cardiac Troponin T Concentration Changes During a Continuous 216-km Marathon. Clin Chem 2009;55:3: 590-2.
  • Gassner D, Stock W, Golla R, Roth HJ. First automated assay for thyrotropin receptor autoantibodies. Clin Chem Lab Med 2009; 47(9):1091-95.
  • Reichenberger MA, Germann G, Roth HJ, Meirer R, Engel H. Preoperative shock wave therapy reduces ischemic necrosis in an epigastric skin flap model. Ann Plast Surg 2009;63(6):1-3.
  • Mettang T, Matterne U, Roth HJ, Weisshaar E. Lacking evidence for calcium-binding protein fetuin-A to be linked with chronic kidney disease-related pruritus (CKD-rP). NTD plus 2009;6:1-2.


  • Roth HJ, Schmidt-Gayk H, Weber H, Niederau CH. Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared to liquid chromatography-tandem mass spectrometry as a reference. Ann Clin Biochem 2008;45:153-159.
  • Roth HJ, Winnefeld D. Neues vollautomatisiertes Nachweisverfahren für TSH-Rezeptor-Antikörper. Management&Krankenhaus 2007; 10: 37.
  • Krause R, Roth HJ, Haas K, Edenharter G, Schober-Halstenberg HJ. Vitamin D-Status bei terminal Nierenkranken in Deutschland. Noeren-Hochdruckkr 2008;37:463.
  • Krause R, Edenharter G, Haas K, Roth HJ, Schober-Halstenberg HJ. Vitamin D-Mangel als Mortalitätsrisiko bei terminal Nierenkranken. Nieren-Hochdruckkr 2008;37:464.
  • Krause R, Roth HJ, Edenharter G, Schober-Halstenberg HJ, Haas K, Fassbinder W, Frei U. Vitamin D deficiency and cardiac mortality in patients on renal replacement therapy (RRT). J Am Soc Nephrol 2008;19:74A.
  • Krause R, Roth HJ, Edenharter G, Schober-Halstenberg HJ. Vitamin D and cancer mortality in patients on renal replacement therapy (RRT). Anticancer Research 2008;28: 1611-1626 (Abstracts of the third international symposium on vitamin D analogs in cancer prevention and therapy. Abstract 16;1619).
  • Thierfelder W, Roth HJ, Laussmann D, Pientka L, Schumacher J, Schulz J, Scheidt-Nave Ch. Vitamin D und Parathormon: Ein Weg zur Bestimmung methodenabhängiger unterer Grenzwerte für Vitamin D. J Lab Med 2008; 32(6): 456-63.


  • Yusof A, Leithauser RM, Roth HJ, Finkernagel H, Wilson MT, Beneke R. Exercise-induced hemolysis is caused by protein modification and most evident during the early phase of an ultraendurance race. J Appl Physiol 2007; 102:582-586.
  • Delanghe JR, Helander A, Wielders JPM, Pekelharing JM, Roth HJ, Schellenberg F, Born C, Yagmur E, Gentzer W, Althaus H. Development and Multicenter Evaluation of the N Latex CDT Direct Immunonephelometric Assay for Serum Carbohydrate-Deficient Transferrin. Clin Chem 2007;53;1115-1121.
  • Verschraegen I, Anchaert E, Schiettecatte J, Mees M, Garrido A, Hermsen D, Lentjes EG, Liebert A, Roth HJ, Stamminger G, Smitz J. Multicenter evaluation of a rapid electrochemiluminescent adrenocorticotropic hormone (ACTH) immunoassay. Clin Chim Acta 2007; 380; 75 – 80.
  • Roth HJ, Leithäuser RM, Doppelmayr H, Doppelmayr M, Finkernagel H, von Duvillard SP, Korff S, Katus HA, Giannitsis E, Benele R. Cardiospecificity of the 3rd generation cardiac troponin T assay during and after a 216 km ultra-endurance marathon run in Detah Valley. Clin Res Cardiol 2007;96;1-6.
  • Schmidt-Gayk H, Roth HJ. Bedeutung von Vitamin D. MTA Dialog 2007;9: 690-1.
  • Fahie-Wilson M, Bieglmayer Ch, Kratzsch J, Nusbaumer C, Roth HJ, Zaninotto M, Plebani M, Hubbuch A, Schneider E. Roche Elecsys Prolaktin II assay: Reactivity with macroprolactzin compared with eight commercial assays for Prolactin and determination of momomeric Prolactin by precipitation with polyethylene glycol. Clin Lab 2007; 53:485-92.
  • Schmidt-Gayk H, Roth HJ. Das Sonnenvitamin – Neues zur Bedeutung von Vitamin D und zur Messung von 25-OH-Vitamin D. Labor&More 2007;3: 48.


  • Lammert M, Friedmann JM, Roth HJ, Friedrich RE, Kluwe L, Atkins D, Schooler T, Mautner VF. Vitamin D deficiency associated with number of neurofibromas in neurofibromatosis 1. J Med Genet 2006 Oct;43(10);810-813.
  • Weber B, Orazi B, Raineri A, Thorstensson R, Bürgisser P, Mühlbacher A, Areal C, Eiras A, Villaescusa R, Camacho R, Diogo I, Roth HJ, Zahn I, Bartel J, Bossi V, Piro F, Atamasirikul K, Permpikul P, Webber L, Singh S. Multicenter Evaluation of a New 4th Generation HIV Screening Assay Elecsys HIV combi. Clin Lab 2006; 52(9-10);463-473.
  • Roth HJ. Prostata-spezifisches Antigen (PSA) Das richtige diagnostische Werkzeug auswählen und sinnvoll einsetzen. Prevention and Anti Aging 2006;2;167-176.


  • Schmidt-Gayk H, Roth HJ. Klinische Wertigkeit der PTH-Bestimmung. Abbott Times 2005;1/05.
  • Schmidt-Gayk H, Jüttner H, Roth HJ, Müller C, Ekiz A, Reichel H. Laborparameter - Zielbereiche bei niereninsuffizienten Patienten. Nephrologie im Dialog 2005; 2/05.
  • Roth HJ. Unusual high levels of ciclosporin in female patient - the impact of lifestyle. Clin Lab 2005;51;425-427.


  • Picker, Scharte LA, Roth HJ, Greve J, Scheeren TWL. Comparison of the role of endothelin, vasopressin and angiotensin in arterial pressure regulation durin sevoflurane anaesthesia in dogs. Br J Anaesth 2004;92(1);102-108.
  • Schmidt-Gayk H, Spanuth E, Kötting J, Bartl R, Felsenberg D, Pfeilschifter J, Raue F, Roth HJ. Perfomance evaluation of automated assays for ß-crosslaps, N-MIS-Osteocalcin and intact parathyroid hormone (BIOROSE Multicenter Study). Clin Chem Lab Med 2004;42(1);90-95.
  • Schmidt-Gayk H, Huber F, Traber L, Roth HJ. Vitamin-D-Versorgung und Marker des Knochenabbaus (ß-Crosslaps) bei prä- und postmenopausalen Frauen. Osteoporose Rheuma 2003;4/03.
  • Kielstein JT, Simmel S, Bode-Böger SM, Roth HJ, Schmidt-Gayk H, Haller H, Fliser D. Subpressor dose asymmetric dimethylarginine modulates renal function in humans through nitric oxide synthase inhibition. Kidney Blood Press Res 2004;27;143-147.
  • Schmidt-Gayk H, Huber F, Roth HJ, Traber L, Reichel H. Beta-crossLaps (CTX) im Plasma zur Erfassung eines gesteigerten Knochenabbaus- Bedeutung der Präanalytik. DBI (Der Bayerische Internist) 2004;3;160.
  • Roth HJ, Schmidt-Gayk H, Niederau C. BNP und NT-proBNP - Bedeutung der Präanalytik. DBI (Der Bayerische Internist) 2004;3;161.
  • Bieglmayer Ch, Chan DW, Sokoll L, Imdahl R, Kobayashi M, Yamada E, Lilje DJ, Luthe H, Meissner J, Messeri G, Celli A, Tozzi P, Roth HJ, Schmidt F-P, Mächler M-L, Schuff-Werner P, Zingler Ch, Smitz J, Schiettecatte J, Vonderschmitt DJ, Pei P, Ng K, Ebert Ch, Kirch P, Wanger M, McGovern M, Stockmann W, Kunst A. Multicentre performance evaluation of the E170 Module for Modular Analytics. Clin Chem Lab Med 2004;42(10);1186-1202.
  • Reichel H, Roth HJ, Schmidt-Gayk H. Evaluation of serum ß-carboxy-terminal cross-linking telopetide of type I collagen as marker of bone resorption in chronic hemodialysis patients. Nephron Clin Pract 2004;98;112-113.
  • Schmidt-Gayk H, Reichel H, Roth HJ, von Gaudecker C, Müller C. Labordiagnostik bei renaler Osteopathie. Osteologie 2004;13;151-163.
  • Coutelle C, Hohn B, Benesova M, Oneta CM, Quattrochi P, Roth HJ, Schmidt-Gayk H, A Schneeweiss, G Bastert, HK Seitz. Risk factors in alcohol associated breast cancer: alcohol dehydrogenase polymorphism and estrogens. Int J Oncol 2004;25(4);1127-1132.


  • Reichel H, Esser A, Roth HJ, Schmidt-Gayk H. Influence of PTH assay methodology on differential diagnosis of renal bone disease. Nephrol Dial Transplant 2003;18;759-768.
  • Muley T, Ebert W, Stieber P, Raith H, Holdenrieder S, Nagel D, Fürst H, Roth HJ, Luthe H, Blijenberg BG, Gurr E, Uhl W, von Pawel J, Drings P. Technical Performance and diagnostic utility of the new elecsys neuron-specific enolase enzyme immunoassay. Clin Chem Lab Med 2003;41(1);95-103.
  • Roth HJ, Albert C, Schmidt-Gayk H. New assay for intact parathyroid hormone and their clinical relevance for the diagnosis of hyperparathyroidism. Clin Lab 2002;48;589-593.
  • Huber F, Traber L, Roth HJ, Heckel V, Schmidt-Gayk H. Markers of Bone Resorption - Measurement in Serum, Plasma or Urine? Clin Lab 2002;49;203-207.
  • Seliger E, Garrido Chercoles A, Hermsen D, Leeser B, Roth HJ, Schiettecatte J. Elecsys SHBG: Results of a multicenter-evaluation. Clin Chem Lab Med 2003;41 (special suppl);S127.


  • Hermsen D, Franzson L, Hoffmann JP, Isaksson A, Kaufman JM, Leary E, Müller Ch, Nakatsuka K, Nishizawa Y, Reinauer R, Riesen W, Roth HJ, Steinmüller T, Troch T, Bergmann P. Multicenter evaluation of a new immunoassay for intact PTH measurement on the Elecsys System 2010 and 1010. Clin Lab 2002;48;131-141.
  • Müller C, Niederle B, Fröhling P, Reichel H, Müller H, Roth HJ, Halleen J, Sammer M, Schmidt-Gayk H. What is the target value for intact PTH in patients on chronic haemodialysis. Balkan Journal of Clinical Laboratory 2002; vol IX;No I.


  • Roth HJ, Zahn I, Alkier R, Schmidt H. Validation of the first automated chemiluminescence protein-binding assay for the detection of 25-hydroxycalciferol. Clin Lab 2001;47;357-365.
  • Krause R, Winter P, Dobberke J, Hopfenmüller W, Roth HJ, Schmidt-Gayk H. Partial body UV(B)-irradiation on dialysis. Photoderm Photoimmunol Photomed 2001;17:143.


  • Roth HJ, Kyriatsoulis A, Hoyle NR. Elecsys Intact PTH assay not affected by the large PTH fragment hPTH(7-84). Clin Lab 2000;46(5-6);295-299.
  • Nussbaum S, Roth HJ. Human-anti-moude-antibodies-pitfalls in tumor marker measurement and strategies for enhanced assay robustness; including results with Elecsys CEA. Anticancer Res 2000;20(6D);5229-5232.
  • Filella X, Friese S, Roth HJ, Nussbaum S, Wehnl B. Technical Performance of the new Elecsys CA 72-4 Test - Development and Field Study. ANtiancer Res 2000;20(6D);5249-5252.


  • Marttunen MB, Hietanen P, Titinen A, Roth HJ, Viinikka L, Ylikorkala O. Effects of tamoxifen and toremifene on urinary excretion of pyridinoline and deoxypyridinoline and bone density in postmenopausal patients with breast cancer. Calcif tissue int 1999;65(5);365-368.
  • Roth HJ, Graf C. Architect i2000 - Ein erster Eindruck. Abbott Times 1999;9;28-31.
  • Schmidt-Gayk H, Roth HJ, Krug A, Kaiser R, Reichel H. Parathormon und nicht-invasive Parameter in der Diagnostik der renalen Osteopathie. Osteologie forum 1999;5;48-58.


  • Roth HJ, Stewart SC, Brawer MK. A comparison of three free and total PSA assays. Prostate Cancer Prostatic Dis 1998;1;326-331.
  • Kunst A, Mc Govern M, Roth HJ. Multicenter evaluation of the Boehringer Mannheim Elecsys 2010 Immunoassay System, hardware and software reliability/practicability of the system. Wien Klin Wochenschrift 1998;110(suppl 3);22-26.
  • Ebert CH, Bieglmayer CH, Igari J, Chan D, Torralba A, Müller CH, Veys A, Bätz O, Dageförde S, Roth HJ, Neumaier D, Assmann G, Banfi GM, Yvert JP. Elecsys TSH, FT4, T4, T-uptake, FT3 and T3. Wien Klin Wochenschrift 1998;110(suppl 3);27-40.
  • Ehrhardt V, Assmann G, Bätz O, Müller CH, Neumeier D, Roth HJ, Veys A, Yvert JP. Results of the multicenter evaluation of an electrochemiluminescence immunoassay for HCG on Elecsys 2010. Wien Klin Wochenschrift 1998;110(supp 3);61-67.


  • Roth HJ, Zahn I. ACS OV: An alternative to well established tests also measuring CA 125? Clin Lab 1997;43;515-526.
  • Schmidt-Gayk H, Bouillon R, Roth HJ. Measurement of vitamin D and its metabolites (calcidiol and calcitriol) and their clinical significance. Scand J Clin Lab Invest 1997;57(suppl 227);35-45.


  • Krause R, Albrecht C, Bühring M Gowin W, Felsenberg D, Bennhold I, Holick M, Chen TC, Schmidt-Gayk H, Roth HJ. Vitamin D-Haushalt und Knochendichte bei Dialysepatienten nach serieller UV-bestrahlung. Phys Rehab Kur Med 1996;6(5):155.
  • Krause R, Albrecht C, Felsenberg D, Gowin D, Bennold I, Bühring M, Schmidt-Gayk H, Roth HJ, Chen TC, Holick MF. Bone mineral density and vertebral morphometry after UV-therapy in hemodialysis patients. Nephrol Dial Transplant 1996;1:1212.
  • Krause R, Albrecht C, Gowin W, Felsenberg D, Bennold I, Bühring M, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ. Knochenmineralgehalt, Vitamin D- und Parathormon-Spiegel während und nach serieller UV-Bestrahlung bei Dialysepatienten. Nieren- Hochdruckkr 1996;25(9):467.
  • Krause R, Klamroth R, Bennold I, Bühring M, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ. Welchen Stellenwert haben Vitamin D und Parathormon in der Blutdruckregulation bei Dialysepatienten. Nieren- Hochdruckkr 1996;25:470
  • Krause R, Matulla B, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ, Bennold I, Bühring M. Regular UV(B)-irradiation. An effective way to normalize calcitriol deficiency in hemodialysis patients. Clin Lab 1996;42:305-7.
  • Huber JM, Roth HJ, Carl P, Hofmann E. Evaluation of ACS PSA2: a new automated assay for the determination of total PSA in Serum. Clin Lab 1996;42;965-968.
  • Gao P, Schmidt-Gayk H, Dittrich K, Nolting B, Maier A, Roth HJ, Seemann O, Reichel H, Ritz E, Schilling T. Immunochemiluminometric assay with two monoclonal antibodies against the N-terminal sequence of human parathyroid hormone. Clin Chim Acta 1996;245(1);39-59.
  • Roth HJ, Zahn I. Schnell zu erlernen, gut zu bedienen, gute Testperformance. Diagnostica Dialog 3/96.


  • H Schmidt-Gayk, Roth HJ, Becker S, Reichel H, Boneth HG, Knuth UA. Noninvasive parameters of bone metabolism. Curr Opin Nephrol Hypertens 1995;4(4);334-338.
  • Krause R, Albrecht C, Felsenberg D, Gowin W, Bennhold I, Bühring M, Schmidt-Gayk H, Roth HJ. Knochenmineralgehalt und Vitamin D-Haushalt unter UV(B)-Bestrahlung bei Dialysepatienten. Nieren- Hochdruckkr 1995;24:511.
  • Krause R, Klamroth R, Bennhold I, Bühring M Schmidt-Gayk H, Roth HJ. Welchen Einfluss hat eine serielle UV-Bestrahlung auf den Vitamin D-Pool und die Vitamin D-Mangelfolgen. Nieren- Hochdruckkr 1995;24:511.
  • Krause R, Bühring M, Bennhold I, Matulla B, Albrecht C, Felsenberg D, Gowin W, Schmidt-Gayk H, Roth HJ, Chen CT, Holick MF. Renale Osteopathie und serielle SUP®-D3-Bestrahlung bei chronischen Hämodialysepatienten. Phys Rehab Kur Med 1995;5:44-5.
  • Krause R, Bennhold I, Matulla B, Klamroth R, Bühring M, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ. Regular UV(B) irradiation in prevention and therapy of vitamin D deficiency in hemodialysis patients. In Biologic Effects of Light 1995 (Ed.MF Holick); Proceedings of a Symposium; Atlanta, USA; Walter de Gruyter.
  • Krause R, Bennhold I, Matulla B, Klamroth R, Bühring M, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ, Boldt F, Kirchner M. Reduction of cardiac risk factors in coronary and hemodialysis patients after UV(B) therapy. In Biologic Effects of Light 1995 (Ed. MF Holick); Proceedings of a Symposium; Atlanta, USA; Walter de Gruyter.
  • Krause R, Bennhold I, Albrecht C, Bühring M, Felsenberg D, Gowin W, Chen TC, Holick MF, Schmidt-Gayk H, Roth HJ, Müller E, Roots I. Bone mineral density, Vitamin D metabolism, and Vitamin D Receptor after UV(B) irradiation in hemodialysis patient. In Biologic Effects of Light 1995 (Ed. MF Holick); Proceedings of a Symposium; Atlanta, USA; Walter de Gruyter.


  • Klaus G, Roth HJ, Ritz E, Mehls O. Single-Dose Oral Calcitriol and Changes of Plasma 1,84iPTH in Uremic Children. Adv Perit Dial 1994;10;261-266.
  • Roth HJ. Validierung des immunradiometrischen Tests "Renin III Generation" zur Erfassung der aktiven Reninkonzentration. Clin Lab 1994;40;1007-1015.
  • Roth HJ, Seibel I, Schmidt B. Muß ein quantitativer EGF-R-Assay die Ligandenbindungsstelle erkennen? Methodenvergleich: Radioligandenbindungsassay(RLBA) vs IEMA- Ligandenbindungsstelle vs IEMA-Nicht-Ligandenbindungsstelle. Clin Lab 1994;1017-1024.


  • Roth HJ. Automation in the Immunoassay Laboratory. Clin Lab 1993;39;108-112.


  • Hoffmann J, Westphal S, Brandhorst G, Rhode KH, Roth HJ, Zahn I, Hintereder G, Scheidner B, Isermann B. Multicenter Evaluation of a New Homocysteine Assay on Roche Clinical Chemistry Analyzers. AACC Los Angeles 2012
  • Jungert A, Roth HJ, Wendt C, Brunner C, Neuhäuser-Berthold M. Vitamin-D-Zufuhr und 25-Hydroxycholecalciferol-Serumspiegel (25(OH)D3) von Senioren der GISELA Studie. 48.Wissenschaftlicher Kongress der DGE, Potsdam, 16.-18.März 2011.
  • Nagel A, Brunner C, Roth HJ, Neuhäuser-Berthold M. Thyreoidea stimulierendes Hormon (TSH) zeigt keinen unabhängigen Einfluss auf den Ruheenergieumsatz euthyreoter Senioren. 48.Wissenschaftlicher Kongress der DGE, Potsdam, 16.-18.März 2011.
  • Young D, Mattke JM, Artus A, Marquet P, Morel-Montero A, Guechot J, Roth HJ. Comparison of Three Methods for Sex Hormone Binding Globulin (SHBG). Clin Chem 2009, 55 (6):D-89 supplement.
  • Jarausch J, Broecker-Preuss M, Casati M, Camara Mas J, van Helden J, Hermsen D, Inomata K, Kratzsch J, Mann K, Miyazaki N, Navarro Moreno M, Murakami T, Roth HJ, Schott M et al. Multicentre evaluation of Elecsys anti-TSHR, a fully automated assay for the determination of TSH receptor autoantibodies (TRAb). AACC 2008, Washington 54,6, supplement C-58 A117
  • Mizera B, Albrecht M, Steinebach I, Roth HJ, , Diziol P, Pfeilschifter J. Assoziation von Serumöstradiol und Knochenstoffwechsel bei frühpostmenopausalen Frauen. P43, Osteologie 2008; 2.-5. April 2008 Hannover, Germany.
  • Gentzer W, Born C, Delanghe J, Helander A, Pekelharing JM, Roth HJ, Schellenberg F, Wielders JPM, Yagmur E. Novel direct fully automated homogenous immunassay for carbohydrate-deficient transferrin (CDT), results of a multicenter study. AACC 2006; Chicago; USA.
  • Roth HJ, RM Leithäuser, H Doppelmayr, M Doppelmayr, H Finkernagel, SP von Duvillard, S Korff, HA Katus, E Giannitsis, R Beneke. Cardiospecificity of the 3rd generation cardiac troponin t assay during and after an ultra-endurance marathon run in the death valley. Congress American College of Cardiology 2006; Atlanta; USA.
  • Bliznakova L, Pelz R, Grimmer Y, Roth HJ, Jennen-Steinmetz C, Schmidt MH, Becker K. Erhöhte CDT-Werte (Carbodefizientes Transferrin) bei Kindern und Jugendlichen mit Essstörungen. XIII Tagung der Biologischen Kinder- und Jugendpsychiatrie 2005; Mannheim; Germany.
  • Leithäuser RM, Doppelmayr H, Doppelmayr M, Finkernagel H, von Duvillard SP, Golding L, Roth HJ, Beneke R. Myocardial stress after Ultra-endurance running in extreme heat. 52nd Annual Congress American College of Sports Medicine 2005; Nashville, USA.
  • Axcell M, Andrews D, Cameron J, Fahie-Wilson M, Hubbuch A, Kratsch J, Roth HJ, Schneider E. Roche Elecsys Prolactin assay: Initial evaluation of a prototype assay with reduced reactivity with macroprolactin. ISOBM 2005; Glasgow; UK.
  • Becker K, Bliznakova L, Grimmer Y, Roth HJ, Jennen-Steinmetz C, Schmidt MH. Carbohydrate-Deficient Transferrin (CDT) in Serum: Preliminary results for children and adolescents. Alcohol Clin Exp Res 2004;28(suppl 8);P12.15;s.35A.
  • Huber F, Traber L, Roth HJ, Zahn I, Heckel V, Schmidt-Gayk H. Markers of bone metabolism and osteoprotegerin in pre- and postmenopausal women – relationship to 25-hydroxy-Vitamin-D. 12. Workshop on Vitamin D 2003 – Maastricht, the Netherlands.
  • Müller C, Fröhling P, Roth HJ, Halleen J, Schmidt-Gayk H. The osteoclastic isoenzyme of tartrate-resistent acid phosphatase (TRAP 5B) in patients on chronic hemodialysis (HD). 9thMeeting of the Balkan Clinical Laboratory Federation 2001; Ioannina, Greece.
  • Lobaugh B, Roth HJ, Seliger E, Pitzel L, Schiettecatte J, Hoffmann JP, Bieglmayer C, Foster AP, Bingenheimer S, Wanger M. An improved assay for estradiol on the Roche Elecsys 1010 and 2010 Immunoassay systems. AACC annual Meeting 2001; Chicago; USA.
  • Schmidt-Gayk H, Traber L, Roth HJ, Lüthgens K, Ebert W. Free and total Pyridinolines as markers of bone metabolism in patients with bone metastases. ISOBM Meeting 2000; USA.
  • Reichel H, Roth HJ, Krug A, Gao P, Schmidt-Gayk H, John MR. Correlation between a novel assay for full-length PTH, intact PTH, TRAP and BAP in adult hemodialysis patients. ASMBR 2000; USA.
  • Domke I, Stieber P, van Helden J, Friese S, van Kamp GJ, Roth HJ, Troalen F, Weisbrich CH, Wollenberg P. Determination of CA 19-9 and CA 15-3 on Elecsys 2010 Immunoanalyzers - Result of a Field Study. AACC 1999; New Orleans; USA.
  • Schmidt-Gayk H, Rieben A, Traber L, Zahn I, Roth HJ. Urinary excretion of Pyridinium Cross-Links in elderly persons is inversely related to Vitamin D status. 10th workshop on Vit D 1997; Strasbourg; France.
  • Tewari P, Roth HJ. Analytical and Clinical Evaluation of ACS free PSA, An Automated Immunoassay to Measure Free PSA in Serum. ISOBM 1996, USA.
  • Roth HJ, Zahn I, Maimonis P. Performance characteristics of ACSBR: a comparison with 3 other assays that also measure CA 15-3. ISOBM 1995, Toronto, Canada.
  • Fuchs D, Zahn I, Roth HJ, Schmidt-Gayk H. Improved competitive Protein-Binding Assay (CPBA) with second Antibody Separation for the Diagnosis of Hyper- and Hypovitaminosis D. VitD congress, Paris 1991.

Contribution to Scientific Meetings:

  • AM Malm, SD Costa, J Huober, Roth HJ, IJ Diel, G Bastert. Comparison of the cancer-associated-serum-antigen (CASA) with CA125. Specificity and sensitivity in benign and malignant disorders. 7. Hamburger Symposium über Tumormarker, Hamburg 1993.


Oral Presentation

  • Roth HJ. Vitamin D measurement – challenges in exact diagnosis, pitfalls, standardization, results of the Elecsys vitamin D total assay. 20th Meeting of Balkan Clinical Laboratory Federation, September 19-22, 2012, Belgrade, Serbia.
  • Hocher B, Armbruster FP, Grön HJ, Stoeva St Lieker I, Slowinski T, Roth HJ. Measuring parathyroid hormone in patients with oxidative stress – Do we need a fourth generation parathyroid hormone assay ? ISN Nexus Symposium 2012 BONE AND THE KIDNEY, Copenhagen, Denmark 2012.
  • Roth HJ. Clinical MSMS - New developments in today's laboratory; Vitamin D: There is a world beyond the bone, and how to gain a reliable insight. IFCC-WorldLab-EuroMedLab Berlin 2011, May 15-19.
  • Schott M, Hermsen D, Broecker-Preuss M, Casati M, Camara Mas J, Eckstein A, Gassner D, Golla R, Graeber C, van Helden J, Inomata K, Jarausch J, Kratzsch J, Miyazaki N, Angel M, Moreno N, Murakami T, Roth HJ, Stock W, Yoshimura Noh J, Scherbaum Wa, Mann K. Clinical value of the first automated TSH receptor autoantibody assay for the diagnosis of Graves’ disease: an international Multicenter trial. 79th Annual Meeting of the American Thyroid Association, Chicago 2008; Oct 1-5.
  • Roth HJ Laborparameter für die Osteoporose-Diagnostik – welche Anforderungen sollen Östradiol- und Vitamin D-Tests erfüllen ? Osteologie 2008, 2. – 5. April; Hannover, Germany
  • Roth HJ, H Schmidt-Gayk: Fecal occult blood test (FOBT) – common guaiac versus immunological Test. 35th meeting of the International Society for Oncodevelopmental Biology and Medicine, ISOBM 2007; Sept. 15-19, S17_A1.
  • R Pelz, L Bliznakova, Roth HJ, Y Grimmer, C Jennen-Steinmetz, MH Schmidt, T Banaschewski, K Becker: Erhöhte CDT-Werte (Carbodefizientes Transferrin) im Serum von Kindern und Jugendlichen mit Essstörungen trotz negativer Alkoholanamnese. XIV. Tagung Biologische Kinder- und Jugendpsychiatrie der DGKJP, 30.11.-1.12.2006 in Hamburg, Abstract S 20.
  • Roth HJ. Trazabilidad en immunoensayos. Simposio internacional Entrenamiento en calidad “Bioquimica Clinica” 2005; Buenos Aires, Argentina.
  • Roth HJ. Control de calidad externo: Una mirada bajo la ISO 15189. Simposio internacional Entrenamiento en calidad “Bioquimica Clinica” 2005; Buenos Aires, Argentina.
  • Roth HJ. Heterophile antibodies and other pitfalls in immunoassays testing. AACB 2004; 10th Asia Pacific Congress of Clinical Biochemistry; Perth; Australia.
  • Roth HJ. Clinical value of cPSA,cPSA/total PSA and free/total PSA in a side by side comparison. ISOBM Edinburgh 2003; Tumor Biology 2003;W11;34.
  • Roth HJ, M Brawer. A comparison of three different manufacturers free and total PSA assays. XIV Congress European Association of Urology 1999.


  • Editor: M Schömig. Die renale Osteopathie. ISBN 3-89599-657-2: 1. Auflage 2005.
  • H Schmidt-Gayk, Roth HJ, A Bregulla, H Reichel, JM Halleen, E Ritz, TB Drücke. Classical serum biochemistry and new biochemical markers. The Spectrum of Renal Osteodystrophy 2001; Oxford University Press.
  • Editors: H Schmidt-Gayk, E Blind, Roth HJ. Calcium Regulating Hormones and Markers of Bone Metabolism: Measurement and Interpretation. Clin Lab Publications, Heidelberg, second edition.