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Publikationsliste Dr. U. Eigner

Development and validation of a bacterial gastrointestinal multiplex RT-PCR assay for use on a fully automated molecular system. Köffer J, Frontzek A, Eigner U, J Microbiol Methods. 2023 May, org/10.1016/j.mimet.2023.106754

Comparison of MICs in Escherichia coli isolates from human health surveillance with MICs obtained for the same isolates by broth microdilution. Suwono B, Hammerl JA, Eckmanns T, Merle R, Eigner U, Lümen M, Lauter S, Stock R, Fenner I, Boemke E, Tenhagen BA. JAC Antimicrob Resist. 2021 Sep 21;3(3):dlab145. doi: 10.1093/jacamr/dlab145.

Decrease in norovirus infections in Germany following COVID-19 containment measures. Eigner U, Verstraeten T, Weil J. J Infect. 2021Feb 10:S0163-4453(21)00076-1. doi: 10.1016/j.jinf.2021.02.012.

Gallbladder Cancer Presenting as Mirizzi Syndrome Complicated by Rapidly Evolving 23 rRNA Gene-Linezolid Resistance with Vancomycin-Resistant Enterococcus Infection Resulting in Fatal Cholangial Sepsis. Schmitz D, Eigner U, Schmidt-Wieland T, Weber P, Magdeburg R, Kienle P, Rudi J. Case Rep Gastroenterol. 2020Oct 28;14(3):540-546. doi: 10.1159/000508851. eCollection 2020 Sep-Dec

Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendations. Nörz D, Frontzek A, Eigner U, Oestereich L, Wichmann D, Kluge S, Fischer N, Aepfelbacher M, Pfefferle S, Lütgehetmann M. J Clin Virol. 2020Nov;132:104650. doi: 10.1016/j.jcv.2020.104650.

Detection of C. difficile toxin as a model assay for performing fully automated high-throughput RT-PCR on clinical stool samples. Eigner U, Nörz D, Reucher S, Furrer J, Sun J, Chu K, Kolb M, Hefner N, Pfefferle S, Lütgehetmann M. J Microbiol Methods. 2020May;172:105882. doi: 10.1016/j.mimet.2020.105882.

Release of Antibiotics Out of a Moldable Collagen-β-Tricalciumphosphate-Composite Compared to Two Calcium Phosphate Granules. Roth KE, Maier GS, Schmidtmann I, Eigner U, Hübner WD, Peters F, Drees P, Maus U. Materials (Basel). 2019 Dec 5;12(24):4056. doi: 10.3390/ma12244056.

Clinical evaluation of multiplex RT-PCR assays for the detection of influenza A/B and respiratory syncytial virus using a high throughput system. Eigner U, Reucher S, Hefner N, Staffa-Peichl S, Kolb M, Betz U, Holfelder M, Spier G, Pfefferle S, Lütgehetmann M. J Virol Methods. 2019Jul;269:49-54. doi: 10.1016/j.jviromet.2019.03.015.

Evaluation of a new real-time PCR assay for the direct detection of diarrheagenic Escherichia coli in stool specimens. Eigner U, Hiergeist A, Veldenzer A, Rohlfs M, Schwarz R, Holfelder M. Diagn Microbiol Infect Dis. 2017 May;88(1):12-16. doi: 10.1016/j.diagmicrobio.2017.01.016. Epub 2017 Feb 1.

Validation of the FluoroType® MRSA assay for the rapid identification of methicillin-resistant Staphylococcus aureus directly from patient material. Eigner U, Veldenzer A, Holfelder M. J Microbiol Methods. 2014Dec;107:71-3. doi: 10.1016/j.mimet.2014.08.007.
Evaluation of six PCR assays in combination with patient related data for the diagnosis of Clostridium difficile-associated infections. Eigner U, Fenner, Veldenzer A, Schwarz K, Oberdorfer K, Holfelder M. Clin Lab. 2014;60(8):1343-50. doi: 10.7754/clin.lab.2013.130735.
Evaluation of the FluoroType MTB assay for the rapid and reliable detection of Mycobacterium tuberculosis in respiratory tract specimens. Eigner U, Veldenzer A, Holfelder M. Clin Lab. 2013;59(9-10):1179-81. doi: 10.7754/clin.lab.2013.121209.
Differentiation of Candida dubliniensis from Candida albicans by means of MALDI-TOF mass spectrometry. Hof H, Eigner U, Maier T, Staib P. Clin Lab. 2012;58(9-10):927-31.
Retrospective evaluation of a PCR based assay for the direct detection of methicillin-resistant Staphylococcus aureus in clinical specimen. Eigner U, Veldenzer A, Fahr AM, Holfelder M. Clin Lab. 2012;58(11-12):1319-21.
Evaluation of a new selective medium, BD BBL CHROMagar MRSA II, for detection of methicillin-resistant Staphylococcus aureus in different specimens. Wendt C, Havill NL, Chapin KC, Boyce JM, Dickenson R, Eigner U, Schütt S, Fahr AM. J Clin Microbiol. 2010 Jun;48(6):2223-7. doi: 10.1128/JCM.02374-09. Epub 2010 Apr 14.

Randomized, double-blind crossover study of vaginal microflora and epithelium in women using a tampon with a "winged" apertured film cover and a commercial tampon with a nonwoven fleece cover. Chase DJ, Schenkel BP, Fahr AM, Eigner U; Tampon Study Group. J Clin Microbiol. 2010 Apr;48(4):1317-22. doi: 10.1128/JCM.00359-09.

Performance of a matrix-assisted laser desorption ionization-time-of-flight mass spectrometry system for the identification of bacterial isolates in the clinical routine laboratory. Eigner U, Holfelder M, Oberdorfer K, Betz-Wild U, Bertsch D, Fahr AM. Clin Lab. 2009;55(7-8):289-96.

High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry-based species identification of nonfermenting bacteria. Mellmann A, Bimet F, Bizet C, Borovskaya AD, Drake RR, Eigner U, Fahr AM, He Y, Ilina EN, Kostrzewa M, Maier T, Mancinelli L, Moussaoui W, Prévost G, Putignani L, Seachord CL, Tang YW, Harmsen D.J Clin Microbiol. 2009 Nov;47(11):3732-4. doi: 10.1128/JCM.00921-09. Epub 2009 Sep 23.

A prospective, randomized, double-blind study of vaginal microflora and epithelium in women using a tampon with an apertured film cover compared with those in women using a commercial tampon with a cover of nonwoven fleece. Chase DJ, Schenkel BP, Fahr AM, Eigner U; Tampon Study Group. J Clin Microbiol. 2007Apr;45(4):1219-24. doi: 10.1128/JCM.02156-06.

Direct detection of methicillin-resistant Staphylococcus aureus in clinical specimens by a nucleic acid-based hybridisation assay. Holfelder M, Eigner U, Turnwald AM, Witte W, Weizenegger M, Fahr A. Clin Microbiol Infect. 2006 Dec;12(12):1163-7. doi: 10.1111/j.1469-0691.2006.01547.x.

Two-center collaborative evaluation of performance of the BD phoenix automated microbiology system for identification and antimicrobial susceptibility testing of gram-negative bacteria. Menozzi MG, Eigner U, Covan S, Rossi S, Somenzi P, Dettori G, Chezzi C, Fahr AM. J Clin Microbiol. 2006Nov;44(11):4085-94. doi: 10.1128/JCM.00614-06.

Spread of ampicillin/vancomycin-resistant Enterococcus faecium of the epidemic-virulent clonal complex-17 carrying the genes esp and hyl in German hospitals. Klare I, Konstabel C, Mueller-Bertling S, Werner G, Strommenger B, Kettlitz C, Borgmann S, Schulte B, Jonas D, Serr A, Fahr AM, Eigner U, Witte W. Eur J Clin Microbiol Infect Dis. 2005 Dec;24(12):815-25. doi: 10.1007/s10096-005-0056-0.
Evaluation of a rapid direct assay for identification of bacteria and the mec A and van genes from positive-testing blood cultures. Eigner U, Weizenegger M, Fahr AM, Witte W. J Clin Microbiol. 2005 Oct;43(10):5256-62. doi: 10.1128/JCM.43.10.5256-5262.2005.

Evaluation of a new molecular system for simultaneous identification of four Enterococcus species and their glycopeptide resistance genotypes. Eigner U, Fahr A, Weizenegger M, Witte W. J Clin Microbiol. 2005 Jun;43(6):2920-2. doi: 10.1128/JCM.43.6.2920-2922.2005.

Analysis of the comparative workflow and performance characteristics of the VITEK 2 and Phoenix systems. Eigner U, Schmid A, Wild U, Bertsch D, Fahr AM.J Clin Microbiol. 2005 Aug;43(8):3829-34. doi: 10.1128/JCM.43.8.3829-3834.2005.

Einfluss der verzögerten Transportdauer bei Raumtemperatur auf die Rate der falsch negativen Blutkulturen im BACTEC™ 9000 Gerät. Impact of delayed entry at room temperature on the rate of false negative blood cultures with the BACTEC™ 9000 instrument. Fahr AM, Eigner Uund Shah PM. J Lab Med 2005;29(2):130–1352005 by Walter de Gruyter•Berlin•New York. DOI 10.1515/JLM.2005.020

Two-center collaborative evaluation of the performance of the BD Phoenix automated microbiology system for identification and antimicrobial susceptibility testing of Enterococcus spp. and Staphylococcus spp. Fahr AM, Eigner U, Armbrust M, Caganic A, Dettori G, Chezzi C, Bertoncini L, Benecchi M, Menozzi MG. J Clin Microbiol. 2003Mar;41(3):1135-42. doi: 10.1128/jcm.41.3.1135-1142.2003.

Evaluation of a new chromogenic medium for the isolation and presumptive identification of Salmonella species from stool specimens. Eigner U, Reissbrodt R, Hammann R, Fahr AM. Eur J Clin Microbiol Infect Dis. 2001 Aug;20(8):558-65. doi: 10.1007/s100960100546.


Publikationsliste Prof. Dr. Peter Findeisen

Krebs von den Lungen-6 as a Potential Predictive Biomarker in Fibrosing Interstitial Lung Diseases. Lederer C, Mayer K, Somogyi V, Kriegsmann K, Kriegsmann M, Buschulte K, Polke M, Findeisen P, Herth F, Kreuter M. Respiration. 2023;102(8):591-600. doi: 10.1159/000531945. Epub 2023 Aug 16.

Proteomic analysis identifies argininosuccinate synthetase 1 and special AT-rich sequence binding protein 1 as reliable markers for the immunohistochemical distinction between WHO types A and B3 thymomas. Bremmer F, Bohnenberger H, Findeisen P, Welter S, von Hammerstein-Equord A, Hinterthaner M, Müller D, Küffer S, Okada S, Marx A, Ströbel P. Histopathology. 2023 Jun 12. doi: 10.1111/his.14972.

Rapid Detection of Lithium Concentrations in Oral Fluid. Granger DA, Parkin GM, Buspavanich P, Findeisen P, Rietschel M, McCarthy MJ, Thomas EA.Ther Drug Monit. 2023 Mar 27. doi: 10.1097/FTD.0000000000001094.
Performance evaluation of cobas pure integrated solutions at multiple sites in Europe and Asia. Hannsjörg Baum, Sail Chun, Peter Findeisen, Hans Fleurkens, Hyunjung Gu, Jinyoung Hong, Franziska Prévôt, Dawid Radziszewski, Michel F. Rossier, Nico Vogt, Jan Furrer, Kai Klopprogge und Christian Schneider-Thauern, Aus der Zeitschrift LaboratoriumsMedizin.

Fluoxetine Enhances Synaptic Vesicle Trafficking and Energy Metabolism in the Hippocampus of Socially Isolated Rats. Filipović D, Costina V, Findeisen P, Inta D. Int J Mol Sci. 2022 Dec 5;23(23):15351. doi: 10.3390/ijms232315351.

A multicenter performance evaluation of the new Elecsys Vitamin D total III assay versus reference isotope dilution liquid chromatography tandem mass spectrometry and commercially available comparators. Findeisen P, Leis M, Bendig G, Grimme J, Moser E, Vogl C, Christenson R. J Clin Lab Anal. 2022 Sep;36(9):e24610. doi: 10.1002/jcla.24610.

Dickkopf 3-A New Indicator for the Deterioration of Allograft Function After Kidney Transplantation. Schuster A, Steines L, Müller K, Zeman F, Findeisen P, Banas B, Bergler T. Front Med (Lausanne). 2022 May 11;9:885018. doi: 10.3389/fmed.2022.885018.

Multicenter Evaluation of a New, Fully Automated Androstenedione Electrochemiluminescence Immunoassay: Precision Analysis, Method Comparison, and Determination of Reference Ranges. Obermayer-Pietsch B, de Ramon M, Reichmuth C, Bendig G, Hutzler S, Taibon J, Rank CM, Findeisen P. J Appl Lab Med. 2022 Mar 2;7(2):503-514. doi: 10.1093/jalm/jfab107.

Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats. Perić I, Costina V, Djordjević S, Gass P, Findeisen P, Inta D, Borgwardt S, Filipović D. Sci Rep. 2021 Sep 7;11(1):17747. doi: 10.1038/s41598-021-97186-7.

Performance evaluation of the Roche Elecsys Anti-SARS-CoV-2 S immunoassay. Riester E, Findeisen P, Hegel JK, Kabesch M, Ambrosch A, Rank CM, Pessl F, Laengin T, Niederhauser C. J Virol Methods. 2021 Nov;297:114271. doi: 10.1016/j.jviromet.2021.114271.


Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2. Riester E, Majchrzak M, Mühlbacher A, Tinguely C, Findeisen P, Hegel JK, Laimighofer M, Rank CM, Schönfeld K, Langen F, Laengin T, Niederhauser C. Infect Dis Ther. 2021 Aug 9:1-17. doi: 10.1007/s40121-021-00504-9.

Intraocular epidermal growth factor concentration, axial length, and high axial myopia. Jonas JB, Dong L, Da Chen S, Neumaier M, Findeisen P, Panda-Jonas S, Jonas RA. Graefes Arch Clin Exp Ophthalmol. 2021 May 29. doi: 10.1007/s00417-021-05200-5.

Specificity testing by point prevalence as a simple assessment strategy using the Roche Elecsys® Anti-SARS-CoV-2 immunoassay. Kittel M, Findeisen P, Muth MC, Thiaucourt M, Gerhards C, Neumaier M, Haselmann V. Int J Infect Dis. 2021 Feb 9:S1201-9712(21)00110-7. doi: 10.1016/j.ijid.2021.02.024.

Clinical evaluation of commercial automated SARS-CoV-2 immunoassays. Kittel M, Muth MC, Zahn I, Roth HJ, Thiaucourt M, Gerhards C, Haselmann V, Neumaier M, Findeisen P. Int J Infect Dis. 2021 Feb;103:590-596. doi: 10.1016/j.ijid.2020.12.003.

Hippocampal synaptoproteomic changes of susceptibility and resilience of male rats to chronic social isolation. Perić I, Costina V, Gass P, Findeisen P, Filipović D. Brain Res Bull. 2021 Jan;166:128-141. doi: 10.1016/j.brainresbull.2020.11.013.
Clinical performance evaluation of a SARS-CoV-2 Rapid Antibody Test for determining past exposure to SARS-CoV-2. Findeisen P, Stiegler H, Lopez-Calle E, Schneider T, Urlaub E, Hayer J, Zemmrich C. Int J Infect Dis. 2021 Feb;103:636-641. doi: 10.1016/j.ijid.2020.11.164.

Tianeptine Enhances Energy-related Processes in the Hippocampal Non-synaptic Mitochondria in a Rat Model of Depression. Perić I, Costina V, Findeisen P, Gass P, Filipović D. Neuroscience. 2020 Dec 15;451:111-125. doi: 10.1016/j.neuroscience.2020.09.061.

Social isolation stress-resilient rats reveal energy shift from glycolysis to oxidative phosphorylation in hippocampal nonsynaptic mitochondria. Filipović D, Perić I, Costina V, Stanisavljević A, Gass P, Findeisen P. Life Sci. 2020 Aug 1;254:117790. doi: 10.1016/j.lfs.2020.117790.
Development of a Mass Spectrometry-Based Method for Quantification of Ustekinumab in Serum Specimens. Scheffe N, Schreiner R, Thomann A, Findeisen P. Ther Drug Monit. 2020 Aug;42(4):572-577. doi: 10.1097/FTD.0000000000000734.
Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib in Liver Metastases of Gastrointestinal Stromal Tumors. Abu Sammour D, Marsching C, Geisel A, Erich K, Schulz S, Ramallo Guevara C, Rabe JH, Marx A, Findeisen P, Hohenberger P, Hopf C. Sci Rep. 2019 Jul 23;9(1):10698. doi: 10.1038/s41598-019-47089-5.

Multicentre evaluation of the Roche Elecsys® Active B12 (holotranscobalamin) electro-chemiluminescence immunoassay. Heil SG, Bodenburg P, Findeisen P, Luebcke S, Sun Y, de Rijke YB. Ann Clin Biochem. 2019 Nov;56(6):662-667. doi: 10.1177/0004563219863818.

Immediate Neutrophil-Variable-T Cell Receptor Host Response in Bacterial Meningitis. Fuchs T, Puellmann K, Dreyfus DH, Piehler AP, Reuter B, Schwarzbach C, Willmann O, Yepes D, Costina V, Findeisen P, Mahrt J, Wang C, Han J, Beham AW, Neumaier M, Kaminski WE. Front Neurol. 2019 Apr 2;10:307. doi: 10.3389/fneur.2019.00307. eCollection 2019.

Comparison of precision and operational performances across six immunochemistry analyzers. Findeisen P, Zahn I, Rabaneda CG, Krempel D, Haro Romero MT, De Haro-Muñoz T, Barral Juez M, Klopprogge K, Engelmann S. Clin Chem Lab Med. 2019 Sep 25;57(10):e248-e252. doi: 10.1515/cclm-2018-1275.
Rapid susceptibility testing of multi-drug resistant Escherichia coli and Klebsiella by glucose metabolization monitoring. Kittel M, Findeisen P, Ghebremedhin B, Miethke T, Grundt A, Ahmad-Nejad P, Neumaier M. Clin Chem Lab Med. 2019 Jul 26;57(8):1271-1279. doi: 10.1515/cclm-2018-1178.
Mass spectrometry based analytical quality assessment of serum and plasma specimens with patterns of endo- and exogenous peptides. Findeisen P, Hemanna S, Maharjan RS, Mindt S, Costina V, Hofheinz R, Neumaier M. Clin Chem Lab Med. 2019 Apr 24;57(5):668-678. doi: 10.1515/cclm-2018-0811.
Spatial Distribution of Endogenous Tissue Protease Activity in Gastric Carcinoma Mapped by MALDI Mass Spectrometry Imaging. Erich K, Reinle K, Müller T, Munteanu B, Sammour DA, Hinsenkamp I, Gutting T, Burgermeister E, Findeisen P, Ebert MP, Krijgsveld J, Hopf C. Mol Cell Proteomics. 2019 Jan;18(1):151-161. doi: 10.1074/mcp.RA118.000980.

Direct MS-Based Bacterial Identification of Blood Cultures. Comparison of an In-House TritonX-Protocol with Bruker-Sepsityper? Kittel M, Greulich A, Findeisen P, Haselmann V, Burrer A, Willem C, Miethke T, Ahmad-Nejad P, Neumaier M. Clin Lab. 2018 Oct 31;64(11). doi: 10.7754/Clin.Lab.2018.180522.
Proteomic characterization of hippocampus of chronically socially isolated rats treated with fluoxetine: Depression-like behaviour and fluoxetine mechanism of action. Perić I, Costina V, Stanisavljević A, Findeisen P, Filipović D. Neuropharmacology. 2018 Jun;135:268-283. doi: 10.1016/j.neuropharm.2018.03.034.
Transforming Growth Factor-β Drives the Transendothelial Migration of Hepatocellular Carcinoma Cells. Koudelkova P, Costina V, Weber G, Dooley S, Findeisen P, Winter P, Agarwal R, Schlangen K, Mikulits W. Int J Mol Sci. 2017 Oct 10;18(10):2119. doi: 10.3390/ijms18102119.

Chronic fluoxetine treatment directs energy metabolism towards the citric acid cycle and oxidative phosphorylation in rat hippocampal nonsynaptic mitochondria. Filipović D, Costina V, Perić I, Stanisavljević A, Findeisen P. Brain Res. 2017 Mar 15;1659:41-54. doi: 10.1016/j.brainres.2017.01.025.
ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER. Costello JL, Castro IG, Hacker C, Schrader TA, Metz J, Zeuschner D, Azadi AS, Godinho LF, Costina V, Findeisen P, Manner A, Islinger M, Schrader M. J Cell Biol. 2017 Feb;216(2):331-342. doi: 10.1083/jcb.201607055.

Alignment of time-resolved data from high throughput experiments. Abidi N, Franke R, Findeisen P, Klawonn F. J Bioinform Comput Biol. 2016 Dec;14(6):1650030. doi: 10.1142/S021972001650030X.
Glycated albumin: from biochemistry and laboratory medicine to clinical practice. Dozio E, Di Gaetano N, Findeisen P, Corsi Romanelli MM. Endocrine. 2017 Mar;55(3):682-690. doi: 10.1007/s12020-016-1091-6.

Clinical applications of MS-based protein quantification. Sabbagh B, Mindt S, Neumaier M, Findeisen P. Proteomics Clin Appl. 2016 Apr;10(4):323-45. doi: 10.1002/prca.201500116.
Functional protease profiling for laboratory based diagnosis of invasive aspergillosis. Sabbagh B, Costina V, Buchheidt D, Reinwald M, Neumaier M, Findeisen P. Int J Oncol. 2015 Jul;47(1):143-50. doi: 10.3892/ijo.2015.2984.

Monoaminylation of Fibrinogen and Glia-Derived Proteins: Indication for Similar Mechanisms in Posttranslational Protein Modification in Blood and Brain. Hummerich R, Costina V, Findeisen P, Schloss P. ACS Chem Neurosci. 2015 Jul 15;6(7):1130-6. doi: 10.1021/cn5003286.
Impact of fumaric acid esters on cardiovascular risk factors and depression in psoriasis: a prospective pilot study. Schmieder A, Poppe M, Hametner C, Meyer-Schraml H, Schaarschmidt ML, Findeisen P, Benoit S, Bauer B, Schmid S, Goebeler M, Goerdt S, Ludwig-Peitsch WK. Arch Dermatol Res. 2015 Jul;307(5):413-24. doi: 10.1007/s00403-015-1541-7.



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